Mass Spectrometric Based Metabolomics of the Saudi Cultivar of Fenugreek ( L.): A Combined GC-MS, Antimicrobial and Computational Approach.

In Saudi Arabia, numerous plant species with promising medicinal properties are cultivated, widely traded, and commonly utilized in traditional medicine, including fenugreek (). This study aimed to comprehensively assess the phytochemical composition and antimicrobial potential of the Saudi cultivar of fenugreek using an integrative approach combining in vitro and in silico methodologies. A comprehensive investigation was conducted on the ethanol extract of fenugreek seeds, assessing its antibacterial, antifungal, properties.

Antioxidant Effects of Moringa oleifera Against Abamectin-Induced Oxidative Stress in the Brain and Erythrocytes of Rats.

The current study was conducted to explore the phytochemical composition and in vitro antioxidant activity of Moringa oleifera leaves aqueous extract (MOLE), as well as its in vivo modulatory effects on abamectin (ABM)-induced oxidative stress in rat erythrocytes and brain tissue. Following extraction, the total phenolic, flavonoid, condensed tannin and ortho-diphenolic contents of MOLE were determined. High-performance liquid chromatography (HPLC) analysis allowed the identification and the quantification of 12 bioactive compounds: gallic acid, chlorogenic acid, caffeic acid, vanillic acid, quercetin, ferulic acid, ascorbic acid, alizarin, hesperidin, neohesperidin, resveratrol, and naringin.

Protective effects of Juglans regia oil on lead acetate-induced reprotoxicity in rats: an antioxidant, histological and computational molecular study.

Background: Lead (Pb) is a metal that affects many body systems, primarily the male reproductive system. This study aimed to examine the phytochemical profiling and beneficial effects of Juglans regia oil (JRO) in alleviating lead-induced reprotoxicity-associated oxidative injury in rats. Adult male Wistar rats were randomly divided into four groups as follows: control group received no treatment, Pb group was exposed to 0.

Experimental exposure of bivalves (Ruditapes decussatus) and meiobenthos (Metoncholaimus pristiurus) to 2,2'4,4'-tetrabromodiphenyl ether (PBDE-47) assessed by biochemical, computational modeling, and microbial tools.

PBDE-47, with lipophilic properties, was found in mussels, clams, and fish where it causes developmental issues, and endocrine and immune disruptions. The current study investigated the effects of PBDE-47 (0.1, 1, and 10 μg.