Publications by authors named "R BOUSQUET"
NiFe-based oxo-hydroxides are highly active for the oxygen evolution reaction but require complex synthesis and are poorly durable when deposited on foreign supports. Herein we demonstrate that easily processable, Earth-abundant and cheap Fe-Ni alloys spontaneously develop a highly active NiFe oxo-hydroxide surface, exsolved upon electrochemical activation. While the manufacturing process and the initial surface state of the alloys do not impact the oxygen evolution reaction performance, the growth/composition of the NiFe oxo-hydroxide surface layer depends on the alloying elements and initial atomic Fe/Ni ratio, hence driving oxygen evolution reaction activity.
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- Omalizumab is a monoclonal antibody that helps treat moderate-to-severe allergic asthma by inhibiting free immunoglobulin E, showing effectiveness mainly in adolescents and adults, but also in children aged 6-12.
- The article reviews various studies focused on the efficacy and safety of omalizumab in young children, discusses its integration into pediatric asthma management guidelines, and examines its pharmacoeconomic aspects.
- Expert commentary suggests that omalizumab is a safe and effective add-on therapy for children aged 6-12 with poorly controlled asthma, especially when used with other medications like corticosteroids and β2-agonists.
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- Breathing in diacetyl (DA) can harm lungs, leading to a serious condition called obliterative bronchiolitis (OB), and this was studied in rats and human airway cells.* -
- Researchers used a special model to see how DA affects airway cells, exposing them to DA vapors multiple times, and found it causes damage and inflammation.* -
- The study showed that DA exposure leads to serious changes in the airway cells, like injury and increased levels of harmful proteins, even without having immune cells come to help.*
Occupational exposure to 2,3-butanedione (BD) vapors has been associated with severe respiratory disease leading to the use of potentially toxic substitutes. We compared the reactivity and respiratory toxicity of BD with that of two structurally related substitutes, 2,3-pentanedione (PD) and 2,3-hexanedione (HD). Chemical reactivity of the diketones with an arginine substrate decreased with increasing chain length (BD > PD > HD).
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