[Application of interrupted normobaric hypoxia stimulation on healthy people].

The INHS application with the practically healthy (sane) people gained the extraordinary widening. This method was theoretically grounded by M.M.

[The prospects for the use of a method of intermittent normobaric hypoxic stimulation (hypoxitherapy) in medical practice].

Hypoxitherapy proposed by Russian researchers promotes a 2-3-fold decrease in morbidity of poor-health subjects (high risk groups). As shown by the experience gained in the medical department of the Moskvich car corporation hypoxitherapy provides enhancement of the human resistance to extreme ecological conditions responsible for high mortality of population in the Russian Federation. The information on the production of special devices, hypoxicators, for creation of hypoxic mixtures (mountain air) is given.

[Manifestation of oxygen effect during normobaric hypoxic hypoxia in the intrauterine and postnatal developmental periods].

The experiments on rats have shown that hypoxic gas mixture containing 10% of oxygen and 90% of nitrogen (HGM-10) under normobaric conditions exerts a highly reliable radioprotective effect on progeny when 11-day pregnant animals are exposed to total irradiation (60Co, 20 Gy). As distinct from the known radioprotector, mexamine, (5-methoxytryptamine), HGM-10 has a pronounced radioprotective effect during the first days (1-5) after birth. Radioresistance of new-born rats correlates with the level of pO2 in the tissues which progressively decreases with respiration of HGM-10 and remains unchanged after mexamine (10 mg/kg) introduction.

[Effect of intermittent normobaric hypoxic activity on the development of acute radiation disease].

The experiments on 260 male mice of colony SHK, 352 mongrel rats and 20 Wistar rats were carried out to study the ability of using the normobaric hypoxic stimulation method for acute radiation sickness. Hypoxic stimulation using gas mixture with 10% of oxygen and 90% of nitrogen was conducted for two weeks after irradiation for 30 min. every day.

[A decrease in the toxic action of x-ray contrast media using normobaric hypoxic stimulation].

A preliminary 30-min action of normobaric hypoxia was found to increase the duration of life of mice treated with lethal doses of billignost, triombrast and verographin. The severity of triombrast-induced pulmonary edema in rats was demonstrated.