Publications by authors named "R B Sothern"

Aim: Measure biomarkers pertinent to autism in saliva from humans.

Materials & Methods: At 7:30 PM (reading instructions) and 8:30 PM (hearing instructions), neurotypical adults (6 M, 6 F) each spat into tubes containing protease inhibitors. Cells were counted, samples aliquoted, frozen and thawed.

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Article Synopsis
  • Researchers conducted a study on the relationship between breast temperature and vascularity in pre-menopausal breast cancer patients and compared them to healthy controls over a 22-year period.
  • The use of a thermometric brassiere (Chronobra) allowed the measurement of breast-associated vascularity during different phases of the menstrual cycle, identifying significant differences in temperature and vascularity among cancer survivors, non-survivors, and healthy women.
  • Findings indicated that breast cancer survivors showed lower vascularity during the luteal phase compared to controls, while non-survivors exhibited higher vascularity, suggesting a potential link between breast temperature patterns and breast cancer outcomes.
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Rationale: There is little knowledge of variations in respiratory symptoms during the menstrual cycle in a general population, and potential modifying factors are not investigated.

Objectives: To investigate menstrual cycle variation in respiratory symptoms in a large general population, using chronobiology methodology, and stratifying by body mass index (BMI), smoking, and asthma status.

Methods: A total of 3,926 women with regular cycles less than or equal to 28 days and not taking exogenous sex hormones answered a postal questionnaire regarding the first day of their last menstruation and respiratory symptoms in the last 3 days.

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Antipsychotic drug therapy, e.g., risperidone, can be associated with endocrine abnormalities, including an increase in serum prolactin level (sPrl) due to a drug-induced benign pituitary tumor (prolactinoma).

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