Water Heater Type, Temperature Setting, Operational Conditions, and Insulation Affect Ecological Niches for Growth.

Residential water heating represents an important nexus of energy/water conservation, waterborne disease, hygiene, and consumer preference. Here, we examine attributes of two off-the-shelf 151-L tank water heaters, one with hot water recirculation (recirculating) and another without recirculation (standard), compared to a tankless on-demand heater (on-demand). Energy efficiency decreased in the order on-demand > standard > continuous recirculation.

IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models.

Interleukin 15 (IL-15) has been evaluated as a potential treatment for solid tumors in clinical trials, but the effectiveness of systemic IL-15 administration as a monotherapy has not been realized. IL-15 receptor alpha (IL-15Rα) can stabilize IL-15 and enhance its bioactivity. The goal of this study was to examine the activity of IL-15/IL-15Rα complex (IL-15cx) to CD8 T cells and evaluate its potential efficacy in murine breast cancer models.

A Vital Layer of Support: One Safety Net Hospital's Palliative Care Response to the Pandemic.

During the coronavirus disease 2019 (COVID-19) pandemic, New York City's public hospitals experienced a significant increase in the number of critically ill patients, especially from minority populations. The palliative care consult service at Bellevue Hospital, therefore, adjusted rapidly to meet the increased needs of our patients and colleagues. To describe the dynamic palliative care needs during a public hospital's COVID-19 surge, including a process to utilize nonpalliative care trained volunteers to meet the increased demand for inpatient palliative care consults.

National Outreach of Telepalliative Medicine Volunteers for a New York City Safety Net System COVID-19 Pandemic Response.

The coronavirus disease 2019 surge in New York City created an increased demand for palliative care (PC) services. In staff-limited settings such as safety net systems, and amid growing reports of health care worker illness, leveraging help from less-affected areas around the country may provide an untapped source of support. A national social media outreach effort recruited 413 telepalliative medicine volunteers (TPMVs).