Publications by authors named "R B Shivappa"

The brown planthopper [ (Stål.)] is one of the most destructive insect pests in all the rice-growing regions of the world. The pest is complicated to manage through the blanket application of chemical pesticides.

View Article and Find Full Text PDF

In manufacturing monoclonal antibodies (mAbs), it is crucial to be able to predict how process conditions and supplements affect productivity and quality attributes, especially glycosylation. Supplemental inputs, such as amino acids and trace metals in the media, are reported to affect cell metabolism and glycosylation; quantifying their effects is essential for effective process development. We aim to present and validate, through a commercially relevant cell culture process, a technique for modeling such effects efficiently.

View Article and Find Full Text PDF

A study was carried out to assess the effect of Stress Coat on slime production in goldfish ( and koi (). The study also investigated histological changes that might be associated with slime producing cells, and wound healing in koi. Several formulations of Stress Coat were investigated and the results showed that polyvinylpyrrolidone (PVP), also known as povidone, an ingredient of Stress Coat, when used alone, showed significantly higher slime production in goldfish than salt and Stress Coat without PVP after 25 h.

View Article and Find Full Text PDF

Human interferon-alpha (huIFN-alpha) is an important immunomodulatory substance used in the treatment and prevention of numerous infectious and immune-related diseases in animals. However, the immunostimulatory effects of huIFN-alpha in fish remain to be investigated. In the current study, the immune responses of the carp species Cyprinus carpio L.

View Article and Find Full Text PDF

Spring viraemia of carp virus (SVCV) is a rhabdovirus associated with systemic illness and mortality in cyprinids. Several diagnostic tests are available for detection of SVCV. However, most of these tests are time consuming and are not well adapted for field-based diagnostics.

View Article and Find Full Text PDF