Publications by authors named "R B Scheffer"
Article Synopsis
- Bovine babesiosis, caused by Babesia bovis and Babesia bigemina, significantly impacts livestock and is often treated with imidocarb in areas lacking vaccines.
- The study involved 15 heifers, with 12 receiving imidocarb and all exposed to ticks to evaluate the development of humoral immunity through seroconversion.
- Results showed that after multiple treatments, a majority of the treated heifers did develop antibodies against the parasites, but not all animals seroconverted, highlighting potential limitations in the effectiveness of the chemoprophylaxis approach.
Article Synopsis
- Gastrointestinal angiodysplasias are vascular abnormalities that can cause severe anemia requiring frequent blood transfusions, and octreotide has been suggested to help reduce rebleeding rates in patients.
- A multicenter, randomized controlled trial compared the effectiveness of octreotide (40 mg every 28 days) to standard care in reducing transfusion requirements over one year for patients with this condition.
- Results showed that patients treated with octreotide required significantly fewer transfusion units (11.0) compared to those receiving standard care (21.2), indicating that octreotide effectively reduces the need for transfusions in these patients.
For non-dysplastic Barrett's Esophagus (BE) patients, guidelines recommend endoscopic surveillance every 3 to 5 years with four-quadrant random biopsies every 2 cm of BE length. Adherence to these guidelines is low in clinical practice. Pooling BE surveillance endoscopies on dedicated endoscopy lists performed by dedicated endoscopists could possibly enhance guideline adherence, detection of visible lesions, and dysplasia detection rates (DDRs).
View Article and Find Full Text PDFIntroduction: Endoscopic ultrasonography guided tissue acquisition (EUS + TA) is used to provide a tissue diagnosis in patients with suspected pancreatic cancer. Key performance indicators (KPI) for these procedures are rate of adequate sample (RAS) and sensitivity for malignancy (SFM).
Aim: assess practice variation regarding KPI of EUS + TA prior to resection of pancreatic carcinoma in the Netherlands.
Barrett Esophagus: Quality of life and factors associated with illness perception.
United European Gastroenterol J
September 2022
Background: Health-related Quality of life (HRQoL) in patients with Barrett's esophagus (BE), a premalignant condition, may be influenced by gastroesophageal reflux disease (GERD) symptoms and the risk of developing esophageal adenocarcinoma.
Methods: We aim to investigate HRQoL in non-dysplastic Barrett Esophagus (NDBE) patients, identify factors associated with a negative illness perception of the diagnosis BE and compare outcomes between patients treated in a specialized BE center with non-expert centers. In this multi-center cross-sectional study, HRQoL of NDBE patients were assessed using the Short Form 36, Hospital Anxiety and Depression Scale, Cancer worry Scale, and Reflux Disease Questionnaire.