Incidence of intravascular uptake during fluoroscopically guided lumbar disc injections: a prospective observational study.

Background: Although there are many in vivo studies evaluating lumbar disc injections, no studies have described the occurrence of intravascular uptake of contrast on discography. This phenomenon, however, has been well documented for other fluoroscopically-guided, contrast-enhanced spinal injections.

Objectives: To document the phenomenon and incidence of intravascular uptake during fluoroscopically-guided, contrast-enhanced lumbar disc injections.

A demographic profile of new traumatic spinal cord injuries: change and stability over 30 years.

Objective: To evaluate epidemiologic trends in new spinal cord injuries (SCIs) in the United States over 3 decades.

Design: Consecutive case series.

Setting: Model Spinal Cord Injury Systems (MSCIS) facilities.

Ep-Cam levels in prostatic adenocarcinoma and prostatic intraepithelial neoplasia.

Purpose: The monoclonal antibody (mAb) 323/A3, a second generation high affinity antibody of the 17-1A antibody family, recognizes a 40 kDa transmembrane glycoprotein that has been referred to as Ep-CAM, 17-1A recognized antigen, or EGP40. While Ep-CAM is expressed on the basolateral surface of a variety of epithelia, the strongest expression is frequently detected among several types of carcinoma. In this regard, Ep-CAM may be useful in therapy, in diagnosis, and/or in prognosis.

Prognostic significance of Bcl-2 expression and p53 nuclear accumulation in colorectal adenocarcinoma.

The products of bcl-2 and p53 genes are involved in the regulation of apoptosis and proliferation and have been associated with prognosis in several malignancies, including colorectal adenocarcinoma. Although 2 European studies have reported a prognostic significance of Bcl-2 expression in colorectal adenocarcinomas, a study from the United States did not observe such an association. Therefore, we used immunohistochemistry to evaluate the prognostic significance of Bcl-2 expression, p53 nuclear accumulation and their concomitant expression in 134 US patients with colorectal adenocarcinoma.