Publications by authors named "R B Mello"
This study integrates proteome analysis of human breast milk (HBM) from a homogeneous group of mothers who are of similar age and live in the same geographical area, along with an analysis of essential and potentially toxic elements in HBM in relation to lifestyle and environmental factors. This preliminary proteomic study, which examined 11 samples of HBM from lactating women, identified a total of 1619 proteins across all samples, revealing significant differences in proteomes influenced by lactation stages, parity, and exposure to tobacco smoke. The pilot study aimed to explore the feasibility of correlating certain proteins with several elements, considered as indicators of tobacco smoke and environmental influences on HBM.
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- Arketamine (R-ketamine) has shown potential for prolonged antidepressant effects and better safety compared to esketamine (S-ketamine), though it has been less studied.
- A review of 20 studies with 410 subjects indicated arketamine's effectiveness for pain management and depression, but many studies were small and informal.
- While arketamine generally has a favorable safety profile, more substantial research is needed to better understand its therapeutic potential and proper clinical usage.
A catalog of Ulidiidae, picture-winged flies, from Chile is provided. Included are all valid names and synonyms for the 16 species and nine genera known from Chile, including information about name, author, year of publication, page number, type species, type locality, and references. Euxesta Loew is the more species richness genus in Chile, with five species, followed by Ceroxys Macquart, with two species.
View Article and Find Full Text PDFA review of Senopterina Macquart, 1835, a Nearctic and Neotropical genus with 21 species, is presented. Senopterina brevipes (Fabricius, 1805), the type species of the genus, and S. macularis (Fabricius, 1805), are redescribed.
View Article and Find Full Text PDFIntroduction: Advanced malignant melanoma is a very aggressive disease, historically with poor prognosis before the new advances with immunotherapy and targeted therapies that have changed the standard of care, especially in cutaneous melanoma. Peru has aggressive features such as higher rates of acral lentiginous melanoma (ALM) subtype with historically shorter survival.
Methods: This study describes Peruvian patients with advanced melanoma treated with immunotherapy (nivolumab) in two oncological institutions (public and private), including the discussion of the impact on overall survival (OS) divided by subtype (with incidence in ALM histology) and potential biomarkers that could be related to prognosis.