Publications by authors named "R B Martini"

Objective: Create and validate the content of video lessons to support nurses when carrying out adolescent consultations in Primary Health Care.

Method: Methodological research carried out in four stages: 1) Exploration, with 83 nurses and two literature narrative reviews; 2) Construction of scripts and storyboards; 3) scripts and storyboards' content validation; 4) Video classes production. Data analysis was conducted using the Content Validity Index.

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COVID-19 pandemic restrictions necessitated curricular modifications in Canadian occupational therapy education. Documentation and reflection on temporary or permanent curriculum modifications and their perceived impact on student learning and outcomes is critical. To explore and compare reported curricula changes (academic and fieldwork) during restricted and post-restricted delivery periods together with the perceived impact on learners.

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Background: Significant advances have been made in targeted therapeutics and systemic therapy regimens for breast cancer (BC) treatment over the past decade. Tumour cells can however remain in the body, leading to locoregional relapse and/or metastasis. Subtypes of BC have distinct prognostic effects and have been linked to varying risks of early locoregional relapse and metastases, response to treatment, and overall survival.

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The integration of machine learning (ML) with radiotherapy has emerged as a pivotal innovation in outcome prediction, bringing novel insights amid unique challenges. This review comprehensively examines the current scope of ML applications in various treatment contexts, focusing on treatment outcomes such as patient survival, disease recurrence, and treatment-induced toxicity. It emphasizes the ascending trajectory of research efforts and the prominence of survival analysis as a clinical priority.

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Article Synopsis
  • Charcot-Marie-Tooth (CMT) type 1 neuropathies are common inherited disorders affecting the peripheral nervous system, with over 100 associated genes identified but lacking effective treatments.
  • A study using Cx32def mice, a model for CMT1X, showed that late-onset voluntary wheel running (VWR) significantly improved functional outcomes, neuromuscular innervation, and axonal health despite advanced disease stages, unlike early-onset exercise which influenced nerve inflammation.
  • The findings suggest that physical exercise could be a promising therapeutic option for CMT1 patients even after the onset of disease symptoms, emphasizing its potential benefits in managing the condition.
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