[Clinical application of dexmedetomidine in patients after thoracic and abdominal surgeries].

Objective: To study efficacy and safety of dexmedetomidine application for long-term (more than 12 hours) artificial lungs ventilation (ALV) and for psychomotor agitation.

Methods: We studied 57 patients after thoracic and abdominal surgeries. The patients were divided into three groups.

[Comparison of analgesics using two devices for the patient-controlled analgesia].

Introduction: A pilot unicenter blind placebo-controlled study comparing different analgesics was conducted in parallel groups, by concurrently using two patient-controlled analgesia (PCA) apparatuses in one patient, was conducted Subjects and methods. The study included patients after laparotomy. Group I patients (n=22) were proposed 2 PCA apparati, one of which contained trimeperidine solution and the other did placebo.

[Does pre-emptive analgesia really pre-empt?].

The paper discusses the theoretical background and practical rationale for a concept of pre-emptive analgesia. It gives the results of studying the efficacy of lornoxicam that outstrips the infliction of a surgical injury in different anesthesia modes (combined total and intravenous combined multicomponent anesthesia with epidural block). A hundred thirty-seven patients who had undergone laparoscopic cholecystectomies (Group 1) and expanded interventions for colorectal cancer (Group 2) were examined.

[Efficacy and safety of lornoxicam in an early postoperative period].

Aim: To compare quality of anesthesia with opioid drug and nonsteroid anti-inflammatory drugs in 123 patients after extensive operative interventions of the lungs and trachea, abdominal organs, lower limbs.

Material And Methods: Patients of group 1 took lornoxicam for relief of postoperative pain syndrome, those of group 2--promedol. Quality of anesthesia was assessed by visual-analogue and verbal scales, day dose of analgetic drug, administration of promedol, side effects incidence.