Direct-to-treatment adaptive radiotherapy: live planning of spine metastases using novel CBCT.

Purpose: CBCT-based online adaptive radiation therapy is carried out using a synthetic CT, sCT, created through deformable registration between the patient-specific fan-beam CT, FBCT, and daily CBCT. Ethos 2.0 allows for plan calculation directly on HyperSight CBCT and uses AI-informed tools for daily contouring without the use of a priori information.

Multi-institutional study on image quality for a novel CBCT solution on O-ring linac.

Introduction: This work presents a multi-institutional study on image quality provided by a novel cone beam computed tomography (CBCT). The main goal is to investigate the consistency of imaging performance across multiple institutions.

Methods: Phantoms for measuring relative electron density (RED) and image quality were sent to six institutions for imaging on Ethos and Halcyon units equipped with HyperSight CBCT.

Handling of missing component information for common composite score outcomes used in axial spondyloarthritis research when complete-case analysis is unbiased.

Background: Observational data on composite scores often comes with missing component information. When a complete-case (CC) analysis of composite scores is unbiased, preferable approaches of dealing with missing component information should also be unbiased and provide a more precise estimate. We assessed the performance of several methods compared to CC analysis in estimating the means of common composite scores used in axial spondyloarthritis research.

Nursing faculty perceptions of entry to nursing practice competencies expected at day one of hire: A statewide study.

Background: No universal nursing education framework exists aligning competency expectations of new-to-practice nurses graduating from the varying prelicensure academic degree programs.

Purpose: This study aimed to identify a set of core competencies expected of all prelicensure nursing programs in Maryland, including associate degree (ADN), entry-level bachelor of science nursing degree (BSN), and master of science entry into nursing (MSN Entry) programs.

Method: A mixed-method approach was used to identify necessary competencies, including a survey consisting of 109 outcome statements and a series of focus groups with faculty representatives from the prelicensure degree programs.

Challenge of missing data in observational studies: investigating cross-sectional imputation methods for assessing disease activity in axial spondyloarthritis.

Objectives: We aimed to compare various methods for imputing disease activity in longitudinally collected observational data of patients with axial spondyloarthritis (axSpA).

Methods: We conducted a simulation study on data from 8583 axSpA patients from ten European registries. Disease activity was assessed by the Axial Spondyloarthritis Disease Activity Score (ASDAS) and the corresponding low disease activity (LDA; ASDAS<2.