Publications by authors named "R B Killian"
Background And Aims: The advantages of endoscopic vs histologic assessments of inflammation in inflammatory bowel disease remain unclear. We compared endoscopic and histologic inflammation in a prospective cohort. Furthermore, in patients with discordant findings, we compared the ability of endoscopy vs histology to predict disease course.
View Article and Find Full Text PDFImportance: Home treatment (HT) has been associated with fewer inpatient treatment (IT) readmission days but lacks evidence on reducing combined psychiatric hospital service use (IT, HT, day clinic).
Objective: To assess the association of intensive home treatment (IHT) compared with IT regarding readmission rate, social outcomes, and clinical outcomes.
Design, Setting, And Participants: This quasi-experimental, nonrandomized trial was conducted from 2020 to 2022 in 10 psychiatric hospitals in Germany.
Article Synopsis
- Crohn's disease (CD) causes chronic inflammation in the intestines, and diet plays a crucial role in shaping the gut microbiome, which might impact CD symptoms.
- A study investigated how a high-fiber, low-fat diet (Mi-IBD) affects gut microbiome function in CD patients over 8 weeks, comparing those who received diet counseling and catered meals.
- The results showed that the Mi-IBD diet improved carbohydrate metabolism in CD patients, with notable differences in microbial function based on whether the disease affected the ileum or colon, benefiting those with colonic involvement the most.
Article Synopsis
- HIV and syphilis are commonly found in sub-Saharan Africa, and a study aimed to look at active syphilis prevalence while factoring in HIV status and demographic details across five countries: Ethiopia, Tanzania, Uganda, Zambia, and Zimbabwe.
- The study involved over 100,000 participants aged 15 and older, who provided demographic and behavioral data along with blood samples for testing. Active syphilis was identified using specific antibody tests, and results were analyzed using statistical models.
- Results showed varying syphilis prevalence rates across the countries, with an estimated 1,027,615 individuals affected; those living with HIV had notably higher syphilis rates compared to those without HIV.
Article Synopsis
- - The study aimed to assess the safety and potential effectiveness of injecting cord blood platelet-rich plasma (CB-PRP) into the eyes of patients suffering from geographic atrophy linked to dry age-related macular degeneration (d-AMD).
- - Thirteen patients participated, with one eye receiving the treatment and the other serving as a control, and outcomes were evaluated over 12 months through various visual and imaging assessments.
- - Results indicated a slight improvement in visual acuity for the treated eyes compared to controls, but the atrophic area increased in both groups and there were no significant complications reported from the procedure.