Publications by authors named "R B Karim"

Background: There is a growing body of data to support the presence of sex disparities in outcomes of cardiovascular related hospitalizations. Despite this, there remains a paucity of data on relationships between sex and in-hospital outcomes in patients receiving a left atrial appendage occlusion device (LAAOD).

Methods: We examined the 2016-2020 Nationwide Readmission Database to identify patients with Atrial Fibrillation receiving a LAAOD.

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The resilience of established business strategies has been tested in the wake of recent global supply chain upheavals triggered by events like the COVID-19 pandemic, Russia-Ukraine combat, Hamas-Israel war, and other geopolitical conflicts. Organizations are compelled to integrate sustainable practices into their supply chains to navigate the complexities of the post-COVID-19 era and mitigate the far-reaching consequences of such disruptions. However, exploring supply chain imperatives from sustainability dimensions still remains underexplored, presenting a significant research gap, particularly in the fashion retail sector.

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  • Hypertensive rats were used to study cardiac hypertrophy and heart failure, focusing on the effects of astaxanthin on oxidative stress, fibrosis, and inflammation.
  • The study induced hypertension in rats using fludrocortisone acetate and salt, showing that astaxanthin treatment reversed markers of oxidative stress and improved antioxidant enzyme activity.
  • Astaxanthin also significantly reduced inflammatory markers and fibrosis in heart and kidneys, suggesting it could help protect against cardiac and renal damage in hypertension through the TGF-β/Smad signaling pathway.
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  • In-hospital cardiac arrest (IHCA) has high rates of morbidity and mortality, with limited understanding of how race/ethnicity and sex impact patient outcomes and treatment.
  • A study analyzed data from over 207,000 IHCA patients, revealing that Black and Hispanic patients had higher mortality rates compared to White males, especially in specific cardiac arrest types.
  • The findings highlight significant disparities in treatment and outcomes based on race and sex, indicating a need for targeted interventions to address these inequities in healthcare.
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