The Ξ_{b}^{0(-)}→Ξ_{c}(3055)^{+(0)}(→D^{+(0)}Λ)π^{-} decay chains are observed, and the spin-parity of Ξ_{c}(3055)^{+(0)} baryons is determined for the first time. The measurement is performed using proton-proton collision data at a center-of-mass energy of sqrt[s]=13 TeV, corresponding to an integrated luminosity of 5.4 fb^{-1}, recorded by the LHCb experiment between 2016 and 2018.
View Article and Find Full Text PDFBreast cancer is a substantial source of morbidity and mortality worldwide. Estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2), are the primary biomarkers which inform breast cancer treatment. Although endocrine therapy for ER+ patients is widely available, there is a need for increased access to low cost, rapid and accurate ER testing methods.
View Article and Find Full Text PDFIntroduction: The number of babies, children and young people with complex care needs (henceforth children with complex care needs (CCCN)) in England has increased in recent decades, and this has also been recognised globally. CCCN may have frequent and lengthy hospital admissions, but during these episodes, their needs are not always met, potentially resulting in suboptimal experiences and outcomes. Despite increased numbers of CCCN accessing acute care and displaying greater complexity, much of the contemporary literature has focused on primary care coordination between health, education and social care.
View Article and Find Full Text PDFBackground: Hospitals increasingly implement complex electronic health record (EHR) systems to improve quality, safety and efficiency. Whilst many aspects surrounding implementation and adoption processes have been researched, the benefits of such enterprise-wide systems may take decades to materialise. Existing work on optimisation processes has focused on technological, workflow and organisational aspects of optimisation within individual clinical settings, mostly in the United States of America.
View Article and Find Full Text PDFThe fundamental skills for motor coordination and motor control emerge through development. Neurodevelopmental disorders such as developmental coordination disorder (DCD) lead to impaired acquisition of motor skills. This study investigated motor behaviors that reflect the core symptoms of human DCD through the use of BXD recombinant inbred strains of mice that are known to have divergent phenotypes in many behavioral traits, including motor activity.
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