Genotypic influence in the juvenile to adult transition in olive seedlings.

Olive breeding is a long process and any improvement in shortening the juvenile phase is highly desirable. In the present study, the effect of olive tree parents in different agronomic characteristics have been evaluated during four years in 520 olive genotypes generated from three different crosses in three different experimental fields, all located in Andalusia region, Spain. The crosses evaluated are 'Arbosana' x 'Sikitita' and its reciprocal, whose parents are characterized by being early bearers; and 'Frantoio' free pollinated, whose mother variety is characterized by having a long unproductive period.

Trisomy 21 as the only recurrent chromosomal anomaly in a clinically aggressive ovarian carcinoma.

A case of a highly aggressive grade III poorly differentiated serous adenocarcinoma of the ovary was determined to exhibit trisomy 21 as the sole chromosomal abnormality. To eliminate the possibility that this trisomy was constitutional, the patient's blood cells were subjected to locus specific 21q22.13 approximately q22.

Establishment and characterization of a poorly differentiated lethal human endometrial carcinoma cell line (NOU-1) with karyotype 46,XX.

Immortal gynecologic cell lines, especially those of endometrial origin are diverse with multiple chromosomal alterations, making the study of origin and molecular genetic characteristics of such neoplasms difficult, if not impossible. We have established a new epithelial, poorly differentiated endometrial adenocarcinoma cell line (NOU-1) with a 46,XX chromosome complement. To confirm the tumor characteristics, we injected this cell line subcutaneously into the nude mouse.

Chromosome analysis and comparison of the benign cystic and malignant squamous component of an ovarian teratoma.

Teratoma, the most common ovarian germ-cell tumor, presumably arises from a single germ cell and is composed of tissues representing all germ layers (ectoderm, mesoderm, and endoderm). Benign cystic teratomas (dermoid cyst) represent over 95% of ovarian teratomas and are comprised of entirely mature adult tissues. When malignant, almost all mature teratomas contain squamous carcinoma.

Karyotypic analysis of 32 malignant epithelial ovarian tumors.

The identification of recurrent specific cytogenetic findings in various malignancies has provided an improved means to diagnose and treat patients. To date, no characteristic markers have been found for epithelial ovarian cancer. This is due, in part, to several contributory factors, including the inability to identify optimal growth conditions for culture and the fact that most analyses of advanced-stage tumors are obtained from malignant effusions rather than from solid tissue.