Publications by authors named "R B Croteau"
Article Synopsis
- Patients with Clostridioides difficile infection (CDI) often have other health issues that need treatments that weaken their immune system.
- The study looked at many research papers to see how these treatments affected the health outcomes of CDI patients.
- It found that patients receiving immunosuppressive therapy had a higher risk of serious problems, like death or needing surgery, compared to those who didn't receive those treatments.
Article Synopsis
- * Cultivated mints have complex genomes and are sterile, making it essential to develop genomic resources from fertile species, leading to the study of Mentha longifolia, a wilt-resistant diploid mint species.
- * The draft genome of M. longifolia includes over 35,000 protein-coding genes and is useful for both metabolic engineering and breeding, with practical applications demonstrated in enhancing essential oil production in peppermint.
Crystal structural data for (4S)-limonene synthase [(4S)-LS] of spearmint (Mentha spicata L.) were used to infer which amino acid residues are in close proximity to the substrate and carbocation intermediates of the enzymatic reaction. Alanine-scanning mutagenesis of 48 amino acids combined with enzyme fidelity analysis [percentage of (-)-limonene produced] indicated which residues are most likely to constitute the active site.
View Article and Find Full Text PDFDevelopment and testing of Spektraris-NMR, an online spectral resource, is reported for the NMR-based structural identification of plant natural products (PNPs). Spektraris-NMR allows users to search with multiple spectra at once and returns a table with a list of hits arranged according to the goodness of fit between query data and database entries. For each hit, a link to a tabulated alignment of (1)H NMR and (13)C NMR spectroscopic peaks (query versus database entry) is provided.
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