Publications by authors named "R B Crandall"
Article Synopsis
- Cervical artery dissection (CeAD) is a leading cause of ischemic strokes in young adults, and this study explored the effects of intravenous thrombolysis (IVT) on patients with CeAD and stroke symptoms.
- Analyzed data from the STOP-CAD study, it found that IVT significantly improved functional independence after 90 days in patients without increasing the risk of symptomatic intracranial hemorrhage.
- The results suggest that IVT is a beneficial treatment for eligible patients with CeAD, aligning with current medical guidelines on its use.
Article Synopsis
- Uncertainty in restoring ecosystems, like southeastern USA pine savannas, can be reduced by studying factors affecting restoration success, particularly through experimental research.
- The study focused on wiregrass (Aristida beyrichiana) and found that competition with native plants and the source of wiregrass seeds significantly impacted its growth and flowering in the first year.
- Results showed that removing competition led to larger wiregrass plants with more flowers, and seeds from wetter sites generally produced more plants, indicating the importance of both seed source and competition in establishing successful wiregrass populations.
Article Synopsis
- PAMAM dendrimers, particularly the generation 4 (G4) version with a fully amine surface, are highly toxic to cells, prompting researchers to modify them for better biocompatibility by introducing neutral hydroxyl groups.
- The modified G4-90/10 dendrimers, with a surface changing to 10% amine and 90% hydroxyl, show less toxicity and effective cellular uptake in various cell types, including neurons and stem cells.
- Studies demonstrate that these dendrimers migrate within the brain after injection, with the G4 variety exhibiting more extensive movement patterns compared to G1 dendrimers, particularly in the anterior, posterior, and lateral directions, along with unique projections to cortical areas.
Overstory trees serve multiple functions in grassy savannas. Past research has shown that understory species can vary along gradients of canopy cover and basal area in savannas. This variation is frequently associated with light availability but could also be related to other mechanisms, such as heterogeneity in soil and litter depth and fire intensity.
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- Positive and negative interactions among species shape the assembly of communities, particularly in dryland plant ecosystems like southeastern U.S. savannas.
- A study of longleaf pine and sandhill oaks revealed that higher oak densities significantly increased the survival and growth rates of longleaf pine seedlings, while lowest recruitment occurred under longleaf pine canopies.
- The findings suggest that conserving and managing xeric oaks can enhance the recovery and sustainability of longleaf pine ecosystems, which are vital for global biodiversity.