Publications by authors named "R Ashton"
Background: Governing bodies of graduate medical education recommend conducting interviews virtually. Although most programs remain compliant with this guidance, it is unclear if this is broadly supported by interviewees. Virtual interview (VI), in-person interview (IPI), and virtual interview with an optional in-person visit (VI+) formats have unique strengths and weaknesses.
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- Neural organoids from human pluripotent stem cells are emerging as powerful tools for exploring CNS development, disease, and drug interactions.
- Despite their promise, many studies on CNS organoids lack effective blood vessel systems, limiting their applicability.
- The review examines current knowledge on vascular development in various CNS regions and emphasizes the need for bioengineering advancements to create more functional vascularized organoid models for research purposes.
Background: Attractive targeted sugar bait (ATSB) stations containing bait (to attract) and ingestion toxicant (to kill) sugar-foraging mosquitoes are hypothesized to reduce malaria transmission by shortening the lifespan of Anopheles vectors.
Methods: A two-arm cluster-randomized controlled trial (cRCT) was conducted in Western Province Zambia. Seventy clusters of 250-350 households were assigned (1:1) by restricted randomization to an intervention arm (ATSB) or control arm (no ATSB) in the context of standard of care vector control (insecticide-treated nets and/or indoor residual spraying).
Background: Some settings continue to experience a high malaria burden despite scale-up of malaria vector control to high levels of coverage. Characterisation of persistent malaria transmission in the presence of standard control measures, also termed residual malaria transmission, to understand where and when individuals are exposed to vector biting is critical to inform refinement of prevention and control strategies.
Methods: Secondary analysis was performed using data collected during a phase III cluster randomized trial of attractive targeted sugar bait stations in Western Province, Zambia.