Characterisation and serodiagnostic evaluation of a recombinant 22.6-kDa tegument protein of .

Schistosomosis in animals due to significantly burdens India's livestock economy because of high prevalence and morbidity and is mostly underdiagnosed from the lack of sensitive tools for field-level detection. This study aimed to clone, express the 22.6-kDa tegument protein of (rSs22.

Exploring eco-friendly approaches for mitigating pharmaceutical and personal care products in aquatic ecosystems: A sustainability assessment.

Global water scarcity is exacerbated by climate change, population growth, and water pollution. Over half of the world's population will be affected by water shortages for at least a month annually by 2050 due toa lack of clean water sources. Even though recycling wastewater helps meet the growing demand, new pollutants, including pharmaceuticals and personal care products (PPCPs), pose a health threat since conventional methods cannot remove them and their environmental monitoring regulations are yet in place.

Isolation and biological evaluation 7-hydroxy flavone from L: insights from extensive , DFT, molecular docking and molecular dynamics simulation studies.

The flavonoid based 7-hydroxy flavone (PubChem CID: 5281894; molecular formula: CHO) molecule has been isolated for the first time from the methanolic extract from the leaves of L. in the tropical mangrove ecosystem of Andaman and Nicobar Islands (ANI), India. The molecular structure of bioactive compound was characterized by spectroscopic analysis, including FT-IR, H, C NMR spectroscopy and ESI-HRMS and elucidated as 7-hydroxy flavone.

Dienaminodioate based multicomponent reactions with post-benzylic oxidative transformations mediated by DDQ.

Multicomponent reactions (MCRs) using dienaminodioate with post-benzylic oxidative transformation mediated by DDQ that afforded a diverse array of products are described. An unprecedented rearrangement of 1,2-dihydropyridines (1,2-DHPs), 3CR products, to 2-pyridones in good yields with a broad substrate scope by DDQ-mediated benzylic oxidation via a pyridinium intermediate is reported. Treatment of the pyridinium intermediate with tert-butyl isocyanide afforded isomerized 1,2-DHPs, analogous to Ritter amides.

Investigations on the membrane interaction of C-terminally amidated esculentin-2 HYba1 and 2 peptides against bacteria.

The membrane interaction and damage caused by C-terminally amidated esculentin-2 peptides identified from the frog skin is illustrated in the present study using and . Double staining with fluorescent probes SYTOX and DAPI proved the concentration-dependent bacterial membrane damage induced by the peptides. It was found that the sub-MIC of both peptides induced transient pores on the bacterial membrane.