Publications by authors named "R Asci"
Objective: This randomized clinical trial study aims to investigate the effects of antioxidant food supplementation on the total antioxidant capacity of seminal plasma, sperm DNA fragmentation, sperm chromatin quality, and semen parameters.
Methods: In this study, a total of 48 subfertile men with moderate physical activity were included. Group 1 was recommended to use the antioxidant supplements, while antioxidant food supplements were not given to Group 2.
Article Synopsis
- The study aimed to evaluate how exogenous testosterone affects choroidal parameters in patients with androgen deficiency compared to healthy individuals.
- Researchers analyzed the eyes of 24 patients with androgen deficiency and 31 healthy volunteers using enhanced-depth imaging optical coherence tomography to measure various choroidal parameters at baseline, 6 weeks, and 18 weeks after treatment.
- Results showed that while some choroidal measurements initially decreased after testosterone treatment, CVI and luminal area significantly increased and remained elevated even four months post-treatment, indicating a lasting effect on the choroidal structure in androgen-deficient patients.
Article Synopsis
- The study examines how metabolic factors, particularly the triglyceride-glucose (TyG) index and visceral adiposity index (VAI), affect male sexual function and erectile dysfunction (ED) in men with sexual dysfunction.
- Higher TyG and VAI levels were linked to an increased risk of ED, with the presence of metabolic syndrome (MetS) further impairing aspects of sexual function.
- The research suggests that TyG and VAI could serve as useful tools for predicting sexual dysfunction, emphasizing the importance of early detection and management of metabolic disorders to improve male sexual health.
Background: Mechanisms by which varicocele causes infertility are not clear and few studies have reported that some miRNAs show expression alterations in men with varicocele. Recently, sperm promoter methylation of MLH1 has been shown to be higher in men diagnosed with varicocele. This study aimed to assess the potential effects of miR-145, which was determined to target MLH1 mRNA in silico on sperm quality and function in varicocele.
View Article and Find Full Text PDFMale infertility is a multifactorial heterogeneous reproductive disorder in which genetic, epigenetic, and environmental factors play a role in the development of disease. Recent studies have shown that retrotransposon expression alterations may be related to impairment of spermatogenesis. Therefore, in this pilot study, we aimed to investigate whether HERV-K6 and HERV-K11 insertional variations have a role in idiopathic infertility among normozoospermic men.
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