Publications by authors named "R Arthi"
Background Blood component transfusion is vital for various medical conditions, requiring thorough pretransfusion testing to ensure safety and compatibility. The Type and Screen (T and S) method allows for efficient detection of clinically significant antibodies while reducing unnecessary crossmatching. This study evaluates T and S's impact on turnaround time and man-hour utilization compared to conventional crossmatching.
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- Hematological malignancies, like acute myeloid leukemia (AML), can lead to severe complications such as hyperleukocytosis, characterized by dangerously high levels of leukocytes (white blood cells) that increase blood viscosity and disrupt circulation.
- A case report details a six-year-old boy with AML who experienced severe hyperleukocytosis, displaying symptoms like high fever and respiratory distress, necessitating urgent medical intervention.
- Therapeutic leukapheresis successfully reduced the patient's leukocyte count by 81% without side effects, leading to significant health improvements and stabilization, highlighting this procedure's critical role in treating pediatric leukemia emergencies.
Article Synopsis
- Blood transfusion services are essential in healthcare, focusing on the identification of seropositive blood donors to enhance the safety of transfusion practices.
- A study spanning 24 months at a southern Indian hospital found that out of 8,276 donations, 117 (1.41%) tested reactive for transfusion-transmitted infections, with hepatitis B being the most prevalent at 0.61%.
- It was revealed that 70% of reactive donors were contacted post-donation, but challenges like inaccurate addresses hindered follow-up, emphasizing the need for accurate information from donors and the importance of post-donation counseling.
Article Synopsis
- Blood donation is crucial for saving lives, especially in emergencies, but many patients, particularly in developing countries, face challenges accessing safe blood due to infrastructure issues and low donor rates driven by cultural beliefs and misconceptions.
- The study aims to evaluate the patterns and causes of blood donor deferrals at a tertiary care hospital over a 36-month period, focusing on identifying the incidence and reasons behind these deferrals.
- Using a cross-sectional retrospective approach, the research analyzes donor demographics, deferral rates among genders, and employs statistical methods to explore potential relationships between gender and deferral rates.
Anti-Lewis antibodies are often not clinically significant since they do not react at 37°C. These antibodies have, however, occasionally been linked to hemolytic transfusion reactions (HTR). We report a case of naturally occurring anti-Lewis-a (Le-a) in a 58-year-old patient found during routine blood grouping.
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