Publications by authors named "R Appleby"
Article Synopsis
- The study compares 'sawtooth' proton arc therapy (PAT) and static intensity modulated proton therapy (IMPT) in terms of their deliverability at a clinical facility.
- It evaluates various PAT plans on different types of targets, including abdominal and brain cases, using both step-and-shoot and continuous delivery methods.
- Results indicate that continuous PAT takes significantly longer in delivery time compared to static IMPT, and while the emulator can model PAT, it shows no evident advantage in beam-on time versus static IMPT, needing further validation.
Radiographic findings in dogs with 360 degrees gastric dilatation and volvulus.
Vet Radiol Ultrasound
January 2025
Article Synopsis
- GDV (Gastric dilatation and volvulus) is a serious medical emergency in dogs, and this study aimed to analyze its radiographic features and how accurately different radiologists can diagnose it.
- The study found that the sensitivity of radiographs to detect 360-GDV was relatively low (43.7%-50%), while the specificity was higher (84.6%-92.1%), indicating some challenges in accurately diagnosing this condition.
- Key radiographic signs unique to 360-GDV included severe esophageal distension and the absence of small intestine swelling, but diagnosing it can be complicated due to similarities with other conditions like gastric dilatation (GD).
Abasic sites are DNA lesions repaired by base excision repair. Cleavage of unrepaired abasic sites in single-stranded DNA (ssDNA) can lead to chromosomal breakage during DNA replication. How rupture of abasic DNA is prevented remains poorly understood.
View Article and Find Full Text PDFBackground: The unsatisfactory rate of Pap tests (PT) is an important quality assurance (QA) metric for a cytopathology laboratory. At our institution, an unsatisfactory PT slide is followed by a second ThinPrep (TP) slide. The aim of this study is to evaluate this QA practice.
View Article and Find Full Text PDFThoracic radiographs are an essential diagnostic tool in companion animal medicine and are frequently used as a part of routine workups in patients presenting for coughing, respiratory distress, cardiovascular diseases, and for staging of neoplasia. Quality control is a critical aspect of radiology practice in preventing misdiagnosis and ensuring consistent, accurate, and reliable diagnostic imaging. Implementing an effective quality control procedure in radiology can impact patient outcomes, facilitate clinical decision-making, and decrease healthcare costs.
View Article and Find Full Text PDF