Publications by authors named "R Aouameur"
Foreign body aspiration in children: experience from 2624 patients.
Int J Pediatr Otorhinolaryngol
October 2013
Objectives: The objective of this study is to analyze the epidemiological, clinical, radiological and endoscopic characteristics of pediatric foreign body aspiration in Algeria.
Methods: In this retrospective study, the results of 2624 children younger than 18 years admitted in our department for respiratory foreign body removal between 1989 and 2012, were presented. Most of them had an ambulatory rigid bronchoscopy.
SMIT2 mediates all myo-inositol uptake in apical membranes of rat small intestine.
Am J Physiol Gastrointest Liver Physiol
December 2007
This study presents the characterization of myo-inositol (MI) uptake in rat intestine as evaluated by use of purified membrane preparations. Three secondary active MI cotransporters have been identified; two are Na(+) coupled (SMIT1 and SMIT2) and one is H(+) coupled (HMIT). Through inhibition studies using selective substrates such as d-chiro-inositol (DCI, specific for SMIT2) and l-fucose (specific for SMIT1), we show that SMIT2 is exclusively responsible for apical MI transport in rat intestine; rabbit intestine appears to lack apical transport of MI.
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- Myo-inositol (MI) plays a key role in cell physiology, particularly in cell signaling and regulating intracellular osmolarity.
- Three MI cotransporters have been identified: two Na(+)-dependent (SMIT1 and SMIT2) and one H(+)-dependent (HMIT), with SMIT2 mainly found in the brain.
- The study found that in rabbit kidneys, SMIT1 is mostly in the medulla, while SMIT2 is predominantly in the cortex, suggesting SMIT2's role in transporting MI into the proximal tubule.