Publications by authors named "R Antonelli-Incalzi"

Background: Poor muscle strength is a risk factor for disability; nonetheless its discriminative capacity in identifying people who will become disabled is poor. We evaluated whether muscle power, which also is a risk factor for disability, has better discriminative capacity compared to muscle strength.

Methods: We used data from the population based InCHIANTI study.

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Background/objectives: there is conflicting evidence on the role of the Mediterranean Diet (MD) in reducing the risk of long-term outcomes in older adults. The aim of our study was to assess the effectiveness of high adherence to MD in reducing all-cause mortality and cardiovascular outcomes among older adults.

Methods: PubMed database was searched up to 31 May 2023.

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Article Synopsis
  • - The study explores in-hospital mortality risk factors for older patients (60+) during the COVID-19 pandemic, emphasizing the ongoing impact of COVID-19 as endemic disease, particularly for those with multiple health issues.
  • - Utilizing data from the Gerocovid-acute wards, researchers incorporated 71 variables into a machine learning platform to identify key prognostic factors affecting mortality, avoiding selection bias and enabling extensive model testing.
  • - The analysis revealed that, alongside traditional health metrics, pre-COVID-19 mobility emerged as a critical predictor of in-hospital mortality, highlighting its importance in risk assessment for older patients.
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  • Trazodone, an antidepressant often prescribed for insomnia, anxiety, and behavioral disorders, is the focus of a study aimed at understanding its prescription reasons, effectiveness, and side effects in older adults in long-term care facilities.
  • The study included feedback from 37 out of 74 participating long-term care facilities, analyzing data from 427 older adults, revealing that common reasons for prescribing trazodone included agitation, insomnia, and depression, with over 90% reporting it was effective.
  • While trazodone proved beneficial, the study identified falls as a key side effect, affecting 30% of participants, underlining the need for careful monitoring in elderly patients, especially those with dementia.
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Perceived health status (PHS) is associated with various health outcomes in older adults, but its relationship with resilience in the context of events with a major impact on functional status (FS), such as hip fracture, has not been explored. Our objective was to evaluate whether older adults who report good PHS before a hip fracture have a higher probability of returning to their baseline physical performance (PP) and personal independence. We analyzed data from waves 1 and 2 of the Survey of Health, Ageing and Retirement in Europe (SHARE) study, enrolling patients ≥ 65 years who experienced a hip fracture between these two waves.

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