Publications by authors named "R Ananda"

Aims: There is conflicting evidence regarding whether excess adiposity without metabolic abnormalities reflects a truly benign phenotype. This study evaluated the independent and joint associations of the presence of excess adiposity and metabolic abnormalities on arterial stiffness.

Materials And Methods: Participants in UK Biobank with body mass index (BMI) and arterial stiffness index (ASI) recorded between 2006 and 2010, free from cardiovascular diseases and not underweight (BMI <18.

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Article Synopsis
  • Primary aldosteronism is linked to increased cardiovascular risks and can affect young adults' arterial health and heart structure before clinical symptoms appear.
  • This study used data from the Raine Study, analyzing young adults at ages 17 and 27 to investigate the relationships between aldosterone levels, arterial stiffness, and left ventricular mass index (LVMI).
  • Results showed that females had higher aldosterone-to-renin ratios than males, and notable associations were found between aldosterone levels and LVMI in males at age 27.
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Introduction: There are currently limited data regarding the clinical and economic significance of skin and soft tissue infections (SSTI) and bone and joint infections in Australian people who inject drugs (PWID).

Methods: Retrospective cohort study in adult PWID admitted to Monash Health, a large heath care network with six hospitals in Victoria, Australia. Inpatients were identified using administrative datasets and International Classification of Disease (ICD-10) coding for specific infection-related conditions.

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Risk of bias (RoB) assessment is essential to the systematic review methodology. The new version of the Cochrane RoB tool for randomized trials (RoB 2) was published in 2019 to address limitations identified since the first version of the tool was published in 2008 and to increase the reliability of assessments. This study analyzed the frequency of usage of the RoB 2 and the adequacy of reporting the RoB 2 assessments in non-Cochrane reviews published in 2020.

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Article Synopsis
  • Primary aldosteronism (PA) is a significant but often overlooked cause of hypertension, leading to preventable harm due to slow diagnosis.
  • An international online survey revealed that 35.6% of participants faced diagnostic delays of five years or more, with women and those having multiple health issues experiencing these delays more frequently.
  • After treatment, 74.4% of patients reported fewer symptoms, and 62.3% experienced improved quality of life, highlighting the need for routine PA screening when hypertension is first diagnosed.
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