Publications by authors named "R Alvarado-Bachmann"
Background: Thyroid nodules are a common clinical condition. Thyroid nodules may be identified with ultrasonography in roughly 50% of the population. The risk of malignancy varies between 4 and 15% of the nodules.
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- Recent advances in understanding the molecular biology of primary colorectal cancer (CRC) have highlighted the role of microsatellite instability (MSI), which is found in about 15% of sporadic cases, but knowledge about colorectal liver metastases (CRLM) is still limited.
- The study analyzed 51 resected CRLM specimens to assess the incidence of MSI by examining immunohistochemical staining for MLH1 and MSH2, aimeding to improve patient selection for potential curative surgeries.
- Results showed no abnormal staining for MLH1 or MSH2 in the specimens, indicating a low incidence of MSI in CRLM, suggesting that MSI may not be a reliable marker for clinical decision-making in this context.
Background: Early inferior pancreaticoduodenal artery (IPDA) ligation reduces intraoperative blood loss during pancreatoduodenectomy, but the impact on oncologic and long-term outcomes remains unknown. The aim of this study was to review the impact of complete pancreatic head devascularization during pancreatoduodenectomy on blood loss, transfusion rates, and clinicopathologic outcomes.
Methods: Clinicopathologic and outcome data were retrieved from a prospective database for all pancreatoduodenectomies performed from April 2004 to November 2010 and compared between early (IPDA+; n = 62) and late (IPDA-; n = 65) IPDA ligation groups.
Pancreatic neuroendocrine tumours (pNETs) are rare and surgical resection offers the only possibility of cure for localised disease. The role of surgery in the setting of locally advanced and metastatic disease is more controversial. Emerging data suggests that synchronous surgical resection of pancreas and liver may be associated with increased survival.
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