To develop and validate a modality-invariant Swin U-Net Transformer (UNETR) deep learning model for liver and spleen segmentation on abdominal T1-weighted (T1w) or T2-weighted (T2w) MR images from multiple institutions for pediatric and adult patients with known or suspected chronic liver diseases. In this IRB-approved retrospective study, clinical abdominal axial T1w and T2w MR images from pediatric and adult patients were retrieved from four study sites, including Cincinnati Children's Hospital Medical Center (CCHMC), New York University (NYU), University of Wisconsin (UW) and University of Michigan / Michigan Medicine (UM). The whole liver and spleen were manually delineated as the ground truth masks.
View Article and Find Full Text PDFBackground: Infectious diseases remain the leading cause of death among children younger than 5 years due to disparities in access and acceptance of essential interventions. The Community Mobilisation and Community Incentivisation (CoMIC) trial was designed to evaluate a customised community mobilisation and incentivisation strategy for improving coverage of evidence-based interventions for child health in Pakistan.
Methods: CoMIC was a three-arm cluster-randomised, controlled trial in rural areas of Pakistan.
Background: Fat mass (FM) and fat-free mass (FFM) in early life are associated with later obesity and cardio-metabolic disease. This study aimed to assess the associations of FM and FFM at birth and conditional FM and FFM accretion from 0-5 years with kidney outcomes at the 10-year follow-up.
Method: The Ethiopian Infant Anthropometry and Body Composition (iABC) birth cohort included term infants born in Jimma town, with a birth weight ≥1500 grams, and having no congenital malformations.
Introduction: E-cigarettes (ECs) and heated tobacco products (HTPs) are recent arrivals to the nicotine product market in the Middle East, which are rapidly growing in popularity in the region. There is a lack of surveillance data at the country-level on use of these products and factors associated with their use.
Methods: This study analyzed a subset of data from the UAE Healthy Future Study, a population-based cohort study of the Emirati population, to determine the factors associated with EC and HTP use among a sample of Emirati adults (≥ 18 years).