Amorphous silica plays an important role in heterogeneous catalysis as a support and is frequently presumed to be "inert". The structure of the supported catalyst is key to understanding the stability and reactivity of catalytic systems. To provide vital insights into the surface reactivity of silica, Polyhedral oligomeric silsesquioxanes (POSSs) can act as realistic homogeneous molecular models for silica surfaces.
View Article and Find Full Text PDFThe beginning of 21 century was marked by an enormous increase in the number of traffic accidents, which led to an increasing number of multiple injured patients with associated injuries, especially injuries of cervical spine, because of its anatomical features. Even in the era of modern diagnostic procedures, cervical spine injuries are still often overlooked, especially in multiple injured patients and unconscious patients, and the consequences of undiagnosed injuries can be fatal. Very often there are ligamentous lesions, which can be detected only by using NMR, while the osteoarticular lesions can be diagnosed through careful clinical examination, X-rays and CT scan.
View Article and Find Full Text PDFBr J Pharmacol Chemother
June 1961
Tyramine is mainly a pressor agent in the rat under urethane, although the hypertensive effect of tyramine in some experiments is followed by a prolonged increase or depression of blood pressure. Bretylium, in doses up to 10 mg/kg, prolonged the response to tyramine, whereas larger doses depressed or blocked its effect. When the hypertensive effect of tyramine was blocked by bretylium, both noradrenaline and dihydroxyphenylalanine, when slowly infused, were found to restore it.
View Article and Find Full Text PDFBr J Pharmacol Chemother
February 1961
Several factors influencing the hypertensive effect of eserine in the rat were investigated. Pretreatment with reserpine regularly depressed or abolished the hypertensive response to eserine. The slow intravenous infusion of either noradrenaline, dihydroxyphenylalanine or 5-hydroxytryptamine only occasionally restored the hypertensive effect of eserine in reserpine-treated rats.
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