Publications by authors named "R Akhavan-Sigari"
Comparing Percutaneous Coronary Intervention and Coronary Artery Bypass Graft in Treatment of Non-ST-segment Elevation Acute Coronary Syndromes: A Systematic Review and Meta-Analysis Study.
Eur J Transl Myol
November 2024
Aims: The objective of this study is to compare the effectiveness and safety of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in the treatment of non-ST-segment elevation acute coronary syndromes (NSTE-ACS).
Methods: A literature search was conducted across PubMed, Scopus, and Web of Science, covering studies up to June 2024. Studies comparing PCI and CABG in patients with NSTE-ACS were included, focusing on clinical outcomes such as mortality, myocardial infarction (MI), cerebrovascular accidents (CVA), and the need for repeat revascularization.
Article Synopsis
- Metabolic dysfunction-associated fatty liver disease (MAFLD) involves fat accumulation in the liver and can progress to severe stages like steatohepatitis and fibrosis, influenced by both environmental and genetic factors.
- Long non-coding RNAs (lncRNAs) are RNA molecules that regulate gene expression and have been linked to various liver diseases, including MAFLD, although their specific roles in this condition remain largely unclear.
- This review highlights recent findings on lncRNAs in MAFLD's development and explores their potential as therapeutic targets for managing this prevalent liver disease.
Although the number of breast cancer deaths has decreased, and there have been developments in targeted therapies and combination treatments for the management of metastatic illness, metastatic breast cancer is still the second most common cause of cancer-related deaths in U.S. women.
View Article and Find Full Text PDFPurpose: Co-administration of microRNAs and chemotherapy drugs effectively treats several cancers. The current study sought to investigate the function of matrix metalloproteinase 16 (MMP16) and miR-193a-5p in the pathogenesis of gastric cancer (GC).
Materials/methods: Sixty-five surgical patients, 15 receiving 5-fluorouracil (5-FU), provided GC and adjacent non-cancerous tissue.
Parkinson's disease (PD) is one of the most frequent age-associated neurodegenerative disorder. Presence of α-synuclein-containing aggregates in the substantia nigra pars compacta (SNpc) and loss of dopaminergic (DA) neurons are among the characteristic of PD. One of the hallmarks of PD pathophysiology is chronic neuroinflammation.
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