Publications by authors named "R Adamo"
Guidelines suggest the Liver Imaging Reporting and Data System (LI-RADS) may not be applicable for some populations at risk for hepatocellular carcinoma (HCC). However, data assessing the association of HCC risk factors with LI-RADS major features are lacking. To evaluate whether the association between HCC risk factors and each CT/MRI LI-RADS major feature differs among individuals at-risk for HCC.
View Article and Find Full Text PDFBackground: We evaluated reporting of diagnostic test accuracy (DTA) systematic reviews using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-DTA and PRISMA-DTA for abstracts.
Methods: We searched MEDLINE for recent DTA systematic reviews (September 2023-Mar 2024) to achieve a sample size of 100. Analyses evaluated adherence to PRISMA-DTA (and abstracts), on a per-item basis.
Article Synopsis
- The study evaluates how the presence of concurrent LR-5 observations impacts the likelihood that LR-3 or LR-4 observations indicate hepatocellular carcinoma (HCC), using a meta-analysis approach.
- The research analyzed data from 29 studies involving 2,591 observations across 1,456 patients, examining the predictive values of LR-3 and LR-4 with and without concurrent LR-5 observations.
- Results showed no significant difference in the positive predictive value for LR-3 and LR-4 observations whether concurrent LR-5 was present or not, suggesting that the presence of LR-5 does not substantially affect HCC diagnosis.
Nevado del Ruiz (Colombia) is infamous for the catastrophic eruption of 1985 that destroyed the villages of Armero and Chinchiná. However, this was not the volcano's first destructive event; similar eruptions also occurred in 1595 and 1845. In 1985, the limited geodetic data available failed to provide a clear warning of the impending eruption.
View Article and Find Full Text PDFGlycoconjugate vaccines are based on chemical conjugation of pathogen-associated carbohydrates with immunogenic carrier proteins and are considered a very cost-effective way to prevent infections. Most of the licensed glycoconjugate vaccines are composed of saccharide antigens extracted from bacterial sources. However, synthetic oligosaccharide antigens have become a promising alternative to natural polysaccharides with the advantage of being well-defined structures providing homogeneous conjugates.
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