Micropallet arrays for the capture, isolation and culture of circulating tumor cells from whole blood of mice engrafted with primary human pancreatic adenocarcinoma.

Circulating tumor cells (CTCs) are important biomarkers of cancer progression and metastatic potential. The rarity of CTCs in peripheral blood has driven the development of technologies to isolate these tumor cells with high specificity; however, there are limited techniques available for isolating target CTCs following enumeration. A strategy is described to capture and isolate viable tumor cells from whole blood using an array of releasable microstructures termed micropallets.

Wake-based unsteady modeling of the aquatic beetle Dytiscus marginalis.

Dytiscus marginalis simultaneously uses its hind legs to propel itself through the water. Previous work has suggested that use of synchronized leg motions, such as that used by D. marginalis, allows it to swim with higher hydrodynamic efficiency than similarly sized insects that alternate their legs during swimming.

Fish schooling as a basis for vertical axis wind turbine farm design.

Most wind farms consist of horizontal axis wind turbines (HAWTs) due to the high power coefficient (mechanical power output divided by the power of the free-stream air through the turbine cross-sectional area) of an isolated turbine. However when in close proximity to neighboring turbines, HAWTs suffer from a reduced power coefficient. In contrast, previous research on vertical axis wind turbines (VAWTs) suggests that closely spaced VAWTs may experience only small decreases (or even increases) in an individual turbine's power coefficient when placed in close proximity to neighbors, thus yielding much higher power outputs for a given area of land.