Publications by authors named "R A Vitti"
Purpose: Identify baseline systemic and ocular characteristics associated with nonproliferative diabetic retinopathy (NPDR) worsening, and the impact of intravitreal aflibercept injection (IAI) on these associations.
Design: Post hoc analysis of PANORAMA.
Participants: Patients with moderately severe to severe NPDR enrolled in the prospective PANORAMA phase 3 trial.
Article Synopsis
- The study aimed to evaluate the flexural strength of dental adhesives by testing different combinations of photoinitiators in their formulation.
- Six groups of adhesive samples were created using specific photoinitiators and co-initiators, and the flexural strength was measured using a three-point testing method.
- Results showed that adhesives containing BAPO and DPIHFP had significantly higher flexural strength than those with CQ and DMAEMA, indicating that these alternative photoinitiators can enhance the performance of dental adhesives.
Importance: Prospective long-term data after retinopathy of prematurity (ROP) treatment with anti-vascular endothelial growth factor injections vs laser therapy are scarce. The FIREFLEYE (Aflibercept for ROP IVT Injection vs Laser Therapy) next trial is prospectively evaluating the long-term efficacy and safety outcomes following ROP treatment with intravitreal aflibercept vs laser therapy.
Objective: To evaluate 2-year ophthalmic and safety outcomes after 0.
There is an urgent need for increased understanding of COVID-19 and strategies for its prevention, treatment, and mitigation. All participants in the research enterprise, including institutional review boards, have an ethical duty to protect participants and ensure that the benefits gained from such research do not conflict with the core principles that guided researchers prior to the pandemic. In this review, we discuss the ethical issues surrounding initiation and conduct of clinical trials, focusing on novel COVID-19 therapeutic, vaccine, or biospecimen research, using the principles of autonomy, beneficence, and justice.
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