Publications by authors named "R A Saadi"

Objective: Our study aims to shed light on racial, ethnic, and geographic disparities in phase 2/3 Meniere's disease (MD) clinical trials, with the ultimate goal of enhancing the inclusivity and effectiveness of future MD research.

Methods: We conducted a systematic review of phase 2/3 MD Randomized Controlled Trials (RCTs). Using the search terms "Meniere's Disease" and "Endolymphatic hydrops", we searched ClinicalTrials.

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Ten percent of children with cancer harbour a mutation in a predisposition gene. In children with the kidney cancer, Wilms tumour, the prevalence is as high as 30%. Certain predispositions are associated with defined histological and clinical features, suggesting differences in tumourigenesis.

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Study Design: Systematic review of the literature.

Objective: The goal of this study is to review and summarize current literature on local flap reconstruction of external auditory canal (EAC) defects.

Methods: PubMed and Ovid databases were queried utilizing search term combinations of "external auditory canal," "defects," "flaps," "local," and "reconstruction.

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Study Design: The study was a retrospective cross-sectional database analysis.

Objective: Deoxycholic acid (DOC) injections are a novel, in-office procedural alternative to submental liposuction or submentoplasty to address excess submental fat. Post-market safety data regarding this treatment is currently limited.

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Article Synopsis
  • IV digoxin loading doses for controlling atrial arrhythmias in critically ill patients lack extensive research, but a loading dose targeting a serum concentration of 0.8-1.5 ng/mL is suggested.
  • A study involving 92 patients found a median loading dose of 11 mcg/kg, resulting in a median serum concentration of 1.3 ng/mL, with 36% experiencing supratherapeutic levels.
  • The study showed that 60% of patients achieved a target heart rate of less than 110 beats per minute within 24 hours, indicating effectiveness in rate control, though further research is needed to validate these results.
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