Publications by authors named "R A R M L N Rajakaruna"
Deferoxamine, deferasirox, and deferiprone triple iron chelator combination therapy for transfusion-dependent β-thalassaemia with very high iron overload: a randomised clinical trial.
Lancet Reg Health Southeast Asia
November 2024
Background: Many patients with β-thalassaemia die prematurely due to iron overload. In this study, we aim to evaluate the efficacy and safety of the triple combination of deferoxamine, deferasirox and deferiprone on iron chelation in patients with transfusion-dependent β-thalassaemia with very high iron overload.
Methods: This open-label, randomised, controlled clinical trial was conducted at Colombo North Teaching Hospital, Sri Lanka.
First record of feline urinary bladder worm (Capillaria syn. Pearsonema) in Sri Lanka: Clinical, histopathological and molecular characterization.
Vet Parasitol Reg Stud Reports
November 2024
Article Synopsis
- The text details a rare case of urinary bladder infection caused by Capillaria in a domestic cat from Sri Lanka, highlighting its uncommon occurrence in pets compared to wild animals.
- The 3-year-old cat exhibited severe symptoms like frequent urination, vomiting, emaciation, and respiratory distress, which led to further medical examination.
- Advanced molecular techniques confirmed the identity of the parasite as Pearsonema, exposing the seriousness of the condition despite the rarity of clinical signs in most cases.
Canine vector-borne infections (CVBIs) are a global health problem. The military working dogs of Sri Lanka die at an early age, and CVBIs have been a leading speculated cause. We examined CVBIs in the working dogs of the Sri Lanka air force (SLAF) and free-roaming dogs (FRDs) and privately owned dogs (PODs) country-wide.
View Article and Find Full Text PDFPurpose: Theileriosis in cattle has a significant economic implication for dairy production globally. Thus, it is crucial to investigate the prevalence of bovine theileriosis, the causative agent and genotypes of Theileria species in dairy cattle in the Kurunegala District in the Intermediate zone, where the third largest population of dairy cattle in Sri Lanka is present and experienced a substantial reduction in the cattle population recently.
Methods: Sixty blood samples and background data were collected from three dairy farms in Galpokuna (n = 20), Koulwewa (n = 20), and Andigama (n = 20) areas.
Purpose: Soil-transmitted nematodes (STNs) are widespread in tropical and subtropical regions, particularly where the communities are socio-economically challenged. We investigated the effect of soil temperature on the prevalence and intensity of STN infection in free-roaming dogs.
Methods: Fresh faecal samples collected from free-roaming dogs in Digana and Pussellawa town areas in the Kandy District, Sri Lanka, were microscopically analysed for canine STNs.