Publications by authors named "R A Pinho"

Objective: To assess sedation following intramuscular (IM) administration of medetomidine versus medetomidine-vatinoxan in bearded dragons.

Study Design: Prospective, randomized, experimental, crossover study.

Animals: A group of 10 (five males and five females) bearded dragons (mean mass ± standard deviation 172 ± 28 g).

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Article Synopsis
  • Physical exercise can help prevent and manage chronic diseases, significantly affecting brain function and metabolism, particularly in conditions like Parkinson's disease, Alzheimer's disease, and epilepsy.
  • The review summarizes findings from a comprehensive literature search, focusing on how exercise influences neuroinflammation, neurotrophic factors, and synaptic plasticity in relation to brain health.
  • It emphasizes that regular physical exercise should be considered a valuable non-drug treatment option for individuals suffering from neurological disorders.
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Background: Veterinarians' approaches to the management of avian pain have been poorly documented despite the rising number of pet birds seen in clinical settings.

Methods: An online survey was advertised nationwide to recruit Brazilian veterinarians who had treated traumatic and surgical conditions in birds within the previous year. The survey comprised 25 closed or semi-closed questions divided into four sections (demographics, routinely performed medical procedures and pain recognition, drug choices for analgesia and challenges to pain treatment, and attitudes towards pain relief in birds).

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Article Synopsis
  • - Addison's disease is a rare condition resulting from damage to the adrenal glands, leading to a deficiency of hormones and presenting with symptoms like fatigue and gastrointestinal issues.
  • - A 36-year-old woman with a history of intestinal obstruction exhibited symptoms including bronzed skin, muscle weakness, and electrolyte imbalances, which led to the diagnosis being confirmed by CT scan showing adrenal calcifications.
  • - Treatment with hydrocortisone and fludrocortisone improved her condition, highlighting the need for awareness and timely diagnosis of Addison's disease for effective hormone replacement therapy and monitoring.
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Diabetic kidney disease (DKD) remains the leading cause of chronic kidney disease (CKD) worldwide. The pathogenesis of DKD is influenced by functional, histopathological, and immune mechanisms, including NLRP3 inflammasome activity and oxidative stress. The sodium-glucose cotransporter 2 inhibitors (SGLT2i) have shown metabolic benefits and the ability to slow the progression of DKD in several clinical studies over the years.

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