Modeling of the structure and forecasting properties of dihydroquercetin derivatives.

Aims: To study new chemical compounds with the potential cure proper, and to develop modifications of the preferred structure of dihydroquercetin.

Background: Producing the new drugs needs the study of the cure properties of the chemical composes first of all, and computer modeling can make this process more informative and easy.

Objective: Computer projection of the chemical compounds' potential cure properties.

Chemical and biological studies on Cichorium intybus L.

Cichorium intybus L. (Asteraceae family) is a world-wide grown plant known as chicory. In traditional medicine, this plant is used as diuretic, anti-inflammatory, digestive, cardiotonic and liver tonic.

[Method of multilayer assembly as alternative to antibacterial coverings of medicobiological implants].

Department of Traumatology and Orthopedics Almaty Kazakh Medical University of Continuing Education; 4. Moscow Regional Research Clinical Institute, Russia Resume: in this report we present the results on the use of the method of layer-by-layer (LbL) for obtaining antimicrobial coatings for biomedical implants. As the substrates were used silicon titanium implants and silicon plate.

[M-cholinergic regulation of Na+,K+-ATPase activity of vesicular preparations of sarcolemma from the myocardium and intestinal smooth muscles].

Acetylcholine (10(-7)-10(-2) M) enhanced the Na+, K+-ATPase activity in sarcolemmal vesicles from myocardium and intestinal smooth muscle. The stimulation of the enzyme from canine ventricles reaches 150% and was less pronounced (10-20%) in the case of frog myocardium and canine ileal muscles. The activating action of the neurotransmitter was simulated by gramicidin D (1-5 microM), but not by valinomycin 1-5 microM), blocked both by ouabain (200 microM) and atropine (0.