[Tick-borne encephalitis associated with other infections].

Possibility of mixed infection arising in encounter of agents from different families (virus-virus, virus-bacteria, virus-protozoa) was demonstrated on 103 cases of chronic tick-borne encephalitis (TBE) association with other acute and chronic infection. The addition of influenza, tuberculosis, pyogenic infection in most cases entails a relapse of TBE or promotes a primary-progressive course of the disease. TBE association with rheumatic fever relieves pain symptoms.

[Characteristics of tick-borne encephalitis virus strains isolated from patients with chronic diseases of the central nervous system].

Two groups of tick-borne encephalitis (TBE) virus strains were studied: Group 1, 5 strains isolated from patients with chronic TBE with progressive course, Group 2, 13 strains isolated from residents of an endemic locality, with chronic diseases of the CNS (amiotrophic lateral sclerosis, epidemic encephalitis, polyoencephalomyelitis, syringomyelia, etc.). Strains of both groups belong to two serotypes of TBE virus: mid-Siberian and Transbaikal (synonym Aina/1448) and eastern.

[Immunological and etiological aspects of a study of the Aina/1448 serotype of the tick-borne encephalitis virus].

Blood sera (1488 specimens) of the human population collected in the zone of isolation of tick-borne encephalitis (TBE) virus strains belonging to the Aina/1448 serotype were tested by the neutralization, hemagglutination-inhibition, agar gel diffusion and precipitation, and complement fixation tests with antigens of the Aina/1448 strain and prototype TBE virus strains representing the eastern and western serotypes. The dominating role of the Aina/1448 serotype in the formation of herd immunity in different areas of the forest-steppe and taiga zones of the Irkutsk region was established. Antibody to the Aina/1448 strain was found in the blood of the normal population and patients with acute and chronic forms of TBE.