[INCIDENCE OF CORONARY HEART DISEASE IN COMBINATION WITH TYPE 2 DIABETES MELLITUS ESTIMATED FROM RESULTS OF AN EPIDEMIOLOGICAL STUDY OF 20-59 YEAR OLD WOMEN].

We report evaluation of the incidence of coronary heart disease (CHD) in combination with type 2 diabetes mellitus (DM2) estimated from results of an epidemiological study of 20-59 year old women. CPD was shown to occur twice more frequently in association with DM2 especilly in the age groups of 30-39 and 50-59 years.

Tyrosinase inhibition studies of cycloartane and cucurbitane glycosides and their structure-activity relationships.

In the present paper, tyrosinase inhibition studies and structure-activity relationship of eight cycloartane glycosides and one cucurbitane glycoside and its genin, which were isolated from Astragalus (Leguminoseae) and Bryonia (Cucurbitaceae) plants, have been discussed. The activities are compared with two reference tyrosinase inhibitors, kojic acid and l-mimosine. These studies and the SAR showed that the askendoside B which exhibited highly potent (IC50 =13.

[Biological and psychosocial factors as a reason for enuresis in children].

Biological (pregnancy in neurotic mothers) and psychosocial (wrong attitude of the family to enuretic child) risk factors were studied in 68 children with enuresis aged 4 to 15 years. It is shown that the presence of biological and psychosocial factors in combination with enuresis in children necessitate antenatal consultations of obstetricians, pediatrists, psychologists and parents on prevention of enuresis in children, active screening-testing children with enuresis for dysfunction of the urinary bladder and psychoneurological disorders affecting harmonic development of personality in children.

[Burden of hereditary diseases in residents of the Mari El Republic].

A summary of the medical genetic studies of the Marii El population is presented. A total of 276,900 people, 110,894 and 166,006 urban and rural inhabitants, respectively, were examined. Regarding the ethnic composition, the studied population was mostly Mari (61.

[A medico-genetic description of inhabitants of two regions of the Kransnodar Krai].

The spectrum and prevalence rate of hereditary pathology in Kanevskii and Bryukhovetskii raions (districts) of Krasnodar krai (territory) were analyzed. The total size of the studied population was 145,937. The prevalence rate of monogenic hereditary pathology was estimated.