MixDeR: A SNP mixture deconvolution workflow for forensic genetic genealogy.

The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. At the same time, and in part because of this advance, there is an intense focus on the generation of SNP profiles from evidentiary specimens for so-called forensic or investigative genetic genealogy (FGG or IGG) applications. However, FGG methods are constrained by the algorithms for genealogical database searches, which were designed for use with single-source profiles, and the fact that many forensic samples are mixtures.

A Walk Through Dementia: exploring the effects of a virtual reality app about dementia on students' knowledge and attitudes.

Background: A Walk Through Dementia (AWTD) is a learning resource that shows dementia from the perspective of people with the condition. Its three 360-degree simulation films depict a person with dementia in different everyday situations and can be viewed online or on a smartphone using an app.

Aim: To evaluate how first-year undergraduate healthcare students react to the AWTD app, what they learn from it and the influence it has on their clinical practice during placements.

Germ cell quantification in human fetal and prepubertal testis tissues - a comparison of current methodologies.

Methods to quantify germ cell number in human immature testicular tissues are essential to evaluate the impact of chemotherapy exposures and for optimising cryopreservation protocols used in fertility preservation for prepubertal boys. Established quantification methods rely on the presence of round tubules within the tissue. However, round tubular cross sections are limited in human prepubertal testicular tissues, especially when using in vitro culture.

The genome sequence of a tachinid fly, (Fallén, 1810).

We present a genome assembly from an individual male tachinid fly, (Arthropoda; Insecta; Diptera; Tachinidae). The genome sequence has a total length of 554.00 megabases.