Publications by authors named "R A Khvoles"

Based on experimental evidence, explicit vorticity-distributed solutions to the Euler equations in two dimensions are constructed describing the tripole vortex. The vortex form and the solution outside the region of nonzero vorticity are derived analytically, while the interior is solved numerically. The continuous-vorticity solution reproduces the main features of the tripoles observed in laboratory experiments and numerical simulations-their shape, flow pattern, and the form of the nonlinear vorticity vs streamfunction relation.

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Transient evoked otoacoustic emissions (TEOAEs) are much used clinically. However, it has been difficult to record them in small laboratory animals, and experimental manipulations designed to determine the generation mechanisms of this type of emission could not be performed. After refining the technique, based on the use of short clicks and a short amplifier gain suppression period, TEOAEs were recorded using the same instrumentation and techniques in rabbits, Psammomys obesus (fat sand rats), mice, rats and guinea pigs.

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There have been reports that the developing ear is more sensitive than the adult ear to noise-induced hearing loss. This was investigated by testing auditory function in rats, both electrophysiologically and histologically, following exposure to broad-band noise (12 h/day for 15 days) at different stages of auditory development (neonates and adults), and also in age-matched controls. An exposure of 90 dB SPL broad-band noise caused no long-term change in auditory function in either age group.

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In order to study the energy dependence of the cochlear amplifier, transient evoked otoacoustic emissions (TEOAEs) and distortion product otoacoustic emissions (DPOAEs) were recorded in rats during gradual cooling to 27 degrees C and heating to 40 degrees C. In the range 33-39 degrees C, the TEOAEs and DPOAEs were maximal in amplitude and almost insensitive to temperature. However, they were significantly depressed (reversibly) at higher and lower temperatures.

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Otoacoustic emissions (OAEs) represent acoustic energy generated by the cochlear amplifier which contributes to auditory sensitivity and frequency discrimination. Therefore the OAEs can serve as a noninvasive tool to study the cochlear amplifier. While transient evoked OAEs (TEOAEs) are generally recorded clinically in man, it has been difficult to record them in animals and instead cubic distortion product OAEs (DPOAEs) have been experimentally studied in animals.

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