Publications by authors named "R A Horowitz"
Article Synopsis
- - Recent studies have found a connection between oral biofilm and the onset or progression of dementia and Alzheimer's disease, often overlooked by the medical community.
- - Coordinating care between physicians and dentists can enhance patient oral health, reduce harmful bacteria, and contribute to overall systemic health.
- - Emphasizing the importance of good oral hygiene and regular dental check-ups can help manage mental health conditions like Alzheimer's and improve patients' quality of life.
Article Synopsis
- Cyclometalated iridium(III) complexes are being explored for use in G-quadruplex (GQ) nucleic acid biosensors, highlighting their potential in biochemistry.
- Through NMR titrations, researchers discovered that the compound [Ir(ppy)(pizp)](PF) significantly affects specific GQ residues, suggesting it mainly binds via end-stacking at the 5' tetrad position.
- Molecular docking and dynamics simulations not only corroborate these findings but also refine the understanding of the binding interactions, indicating their effectiveness in predicting binding sites for experimental contexts.
Background: In non-nephrology settings, specialty Palliative Care (PC) improves decision-making, patient's quality of life (QoL), advance care planning (ACP), and certain indicators of the quality of end-of-life (EoL) care. This pilot RCT explored the feasibility and acceptability of a PC intervention, CKD-EDU, for older adults ≥75 years with eGFR ≤25 ml/min and their caregivers.
Methods: Participants randomized to the control group received standard nephrology care and routine kidney therapy (KT) education, while those randomized to CKD-EDU received a decision aid and met with a PC clinician up to three times to discuss KT decisions and EoL planning.
Protocol to Develop a Core Outcomes Set for Peripheral Nerve Injury.
J Hand Surg Asian Pac Vol
February 2025
Article Synopsis
- * The aim is to establish a core outcome set for evaluating PNI treatments by first reviewing current reporting methods and then using the Delphi process for consensus on important outcome measures.
- * The Delphi process will include two online rounds for gathering opinions and one in-person round to finalize the measures, leading to a standardized way to report outcomes that enhances collaboration and research in the field.
Electrical Stimulation: Enhancing Axonal Growth following Peripheral Nerve Injury.
J Hand Surg Asian Pac Vol
October 2024
Electrical stimulation has been integrated in recent decades into rehabilitation protocols following neuromuscular injuries. Existing literature supports the utilisation of prolonged or continuous stimulation generated by implantable or transcutaneous devices for chronic pain subsidence and muscle trophism maintenance, which improve outcomes following microsurgical interventions. Newer uses include brief electrical stimulation for peripheral nerve injury.
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