Comparative genomics between and : CAZymes and candidate virulence factors.

Introduction: The oral trichomonad is increasingly appreciated as a likely contributor to periodontitis, a chronic inflammatory disease induced by dysbiotic microbiota, in humans and domestic animals and is strongly associated with its worst prognosis. Our current understanding of the molecular basis of interactions with host cells and the microbiota of the oral cavity are still rather limited. One laboratory strain of T.

A Conserved Ribosomal Protein Has Entirely Dissimilar Structures in Different Organisms.

Ribosomes from different species can markedly differ in their composition by including dozens of ribosomal proteins that are unique to specific lineages but absent in others. However, it remains unknown how ribosomes acquire new proteins throughout evolution. Here, to help answer this question, we describe the evolution of the ribosomal protein msL1/msL2 that was recently found in ribosomes from the parasitic microorganism clade, microsporidia.

Evolutionary conservation of mycoplasma symbiosis across the host species barrier.

Introduction: The protozoan parasite is the most common cellular sexually transmitted disease in humans, and the closely related species is an avian parasite of ecological and economic importance. Phylogenetic evidence suggests arose during bird to human transmission of a -like ancestor. shares a strong clinical association with the independent sexually transmitted pathogen (formerly ) , and the uncultured bacterium " Malacoplasma (formerly ) girerdii," with the latter association being an order of magnitude stronger.

NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli.

Trichomonas vaginalis is a human protozoan parasite that causes trichomoniasis, a prevalent sexually transmitted infection. Trichomoniasis is accompanied by a shift to a dysbiotic vaginal microbiome that is depleted of lactobacilli. Studies on co-cultures have shown that vaginal bacteria in eubiosis (e.