Publications by authors named "R A Gasser"
SCREEN: A Graph-based Contrastive Learning Tool to Infer Catalytic Residues and Assess Enzyme Mutations.
Genomics Proteomics Bioinformatics
December 2024
Unlabelled: The accurate identification of catalytic residues contributes to our understanding of enzyme functions in biological processes and pathways. The increasing number of protein sequences necessitates computational tools for the automated prediction of catalytic residues in enzymes. Here, we introduce SCREEN, a graph neural network for the high-throughput prediction of catalytic residues via the integration of enzyme functional and structural information.
View Article and Find Full Text PDFArticle Synopsis
- - Human strongyloidiasis is often misdiagnosed due to a lack of awareness about the crucial developmental stages of the parasite, particularly the fourth-stage larvae (L4a).
- - This study reports the successful identification of these L4a larvae in two clinical cases in Australia using direct wet-mount microscopy methods on sputum and bronchoalveolar lavage samples.
- - It highlights important morphological characteristics of L4a, such as its conical tail and mature genital features, to improve diagnostic accuracy for parasitological laboratories.
This article examines the major transformation within the higher education sector, specifically the shift from traditional academia to neoliberal academia, with an emphasis on its impact on academics who entered the field in the 2000s. Many of these individuals may not fully recognise the extensive political and structural changes driven by neoliberalism over the past 2 decades. Published literature shows how the widespread adoption of managerialism in a neoliberal context-particularly in the Anglo-Saxon world-has markedly altered the academic landscape.
View Article and Find Full Text PDF