Publications by authors named "R A Fenstermaker"
Patients with high-grade glioma (HGG) have an extremely poor prognosis compounded by a lack of advancement in clinical care over the past few decades. Regardless of classification, most newly diagnosed patients receive the same treatment, radiation and temozolomide (RT/TMZ). We developed a functional precision oncology test that prospectively identifies individual patient's response to this treatment regimen.
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- * It involved seven patients with different brain conditions, utilizing contrast clearance analysis (CCA) during MRI to assist in clinical decision-making and comparing those results with surgical histopathology findings.
- * The results showed a 100% concordance rate between CCA and histopathology, suggesting that CCA is a reliable tool for diagnosing issues related to brain tumors and can significantly influence treatment plans and patient outcomes.
Article Synopsis
- Survivin is a special protein found in many cancer cells, especially in lung cancer, and helps those cells survive longer.
- Researchers are studying how survivin works with other genes and proteins to help improve lung cancer treatments, including new vaccines and immune therapies.
- A lot of research has been done to find ways to target survivin to help fight lung cancer and improve the chances of successful treatment.