Publications by authors named "R A Cordeiro"
Mpox is a zoonotic disease caused by the Monkeypox virus (MPXV), and since May 2022, tens of thousands of cases have been reported in non-endemic countries. We aimed to evaluate the suitability of different sample types for mpox diagnostic and assess the temporal dynamics of viral load. We evaluated 1914 samples from 953 laboratory-confirmed cases.
View Article and Find Full Text PDFObjective: To evaluate the cardiac involvement in patients with Still's disease with a focus on myocarditis included in the multicenter AIDA (AutoInflammatory Disease Alliance) network Still's disease registry. To exploit the predictive factors for myocarditis in deriving a clinical risk patient profile for this severe manifestation.
Methods: A multicenter observational study was built up assessing consecutive patients with Still's disease characterized by the cardiac involvement among those included in the AIDA Network Still's Disease Registry.
Geraniol inhibits both planktonic cells and biofilms of the Candida parapsilosis species complex: Highlight for the improved efficacy of amphotericin B, caspofungin and fluconazole plus Geraniol.
Med Mycol
November 2024
Article Synopsis
- The Candida parapsilosis species complex is a significant concern in healthcare settings due to rising antifungal resistance.
- Geraniol, a terpene from essential oils, has demonstrated potential antimicrobial effects against this yeast species in both planktonic and biofilm forms.
- In lab tests, geraniol showed an effective minimum inhibitory concentration (MIC) between 256-512 µg/ml and reduced biofilm activity, while also enhancing the effectiveness of certain antifungal medications like amphotericin B and fluconazole.
Antimicrobial and antibiofilm effect of promethazine on bacterial isolates from canine otitis externa: an in vitro study.
Microb Pathog
November 2024
Article Synopsis
- Otitis externa is a condition in dogs where the external ear canal becomes inflamed, usually due to bacterial infections, and this study focuses on testing promethazine's effectiveness against it.
- * The research evaluated how promethazine affects bacterial growth and biofilm formation over 120 hours, determining its minimum inhibitory concentrations (MIC) and minimum biofilm eradication concentration (MBEC).
- * Results showed that promethazine significantly reduced biofilm growth and could be a promising treatment for recurring bacterial otitis in dogs, highlighting the benefits of repurposing existing drugs to combat antimicrobial resistance.