Estrogen receptor polymorphism, estrogen content and idiopathic scoliosis in human: a possible genetic linkage.

Idiopathic scoliosis (IS) is a largely diffused disease in human population but its pathogenesis is still unknown. There is a relationship between scoliotic phenotype and the patient age, since in the early stage the pathology shows a ratio of 50% between male and female teenagers. During puberty the sex ratio is 8.

[Laparoscopic cholecystectomy. Our experience].

Background And Aims: The authors analyse their first two years of experience regarding the use of laparoscopic cholecystectomy and report the results of this series and their observations.

Methods: A total of approximately 200 cholecystectomies have been performed using a laparoscopic technique at S. Paolo Hospital in Naples (Department of Surgery; Head: Prof.

[Colonic angiodysplasia: an important cause of digestive hemorrhage].

Angiodysplasia of the colon is one of the most common causes of lower gastrointestinal bleeding in elderly patients. The diagnosis can be made by colonscopy or angiography. The best treatment, endoscopic coagulation or surgical resection, is still being debated.

[Leiomyosarcoma of the mesenteric root. A case report].

Although smooth muscle tumors are the most common mesentery neoplasms, they are lesions of infrequent occurrence. The main clinical features of these malignancies are an insidious onset and an aspecific symptomatology, usually presenting themselves as quite large masses. The preoperative diagnosis is difficult, but selective angiography and CT scan may be of great value for this purpose.

Combined effects of immunity and antitumor drugs against cancer. II. In vitro studies with cis-diamminedichloroplatinum in a human leukemia system.

Human K562 leukemic cells were exposed in vitro to cis-diamminedichloroplatinum (DDP) followed by addition of intact or irradiated mononuclear cells (MNC) obtained from peripheral blood of normal donors. tumor inhibition provoked by DDP was significantly enhanced by normal MNC, but not by irradiated cells at the effector: leukemic cell ratio of 2:1. In contrast MNC alone did not show appreciable effects on K562 cells.