ASSESSMENT OF ADEQUATE IODINE AVAILA-BILITY TO THE POPULATION OF WEST KAZAKHSTAN BASED ON THE DATA OF INORGANIC IODINE IN URINARY EXCRETION.

Aim of research - to study the iodine supply of the region according to the degree of urinary iodine excretion in the West region of the Republic of Kazakhstan. Of 6493 schoolchildren participating in the study of the frequency of goiter, random sampling was applied to select 884 children to determine UIC. To establish the excretion of inorganic iodine in a single portion of urine in the field, express diagnostics, the "Iodine test" kits (manufactured in Ukraine), was applied.

[MICROELEMENT STATUS IN CHILDREN WITH ENLARGED THYROID GLAND IN WEST KAZAKHSTAN REGION].

Aim of research - analysis of content of microelements in hair of children with thyromegaly living in the West Kazakhstan region. 159 school children of 6-12 years constantly living in this region were studied. Thyroid volume was measured by ultrasonography using an ultrasound scanner and evaluated according to body surface area and the gender in accordance with the WHO recommendations (2007).

Mycobacterium bovis isolates with M. tuberculosis specific characteristics.

Our study is the first report of exceptional Mycobacterium bovis strains that have some characteristics of M. tuberculosis. The strains were isolated from 8 patients living in Kazakhstan.

Rifampicin and isoniazid resistance mutations in Mycobacterium tuberculosis strains isolated from patients in Kazakhstan.

Objective: To analyse possible associations of specific mutations conferring rifampicin (RMP) and isoniazid (INH) resistance with Beijing and non Beijing genotype strains of Mycobacterium tuberculosis from Kazakhstan.

Method: Genotypic analysis of 92 multidrug-resistant (MDR), 50 INH but not RMP-resistant (INHr/RMPs) and 10 fully susceptible strains of M. tuberculosis from Kazakhstan was performed.

The Beijing genotype is a major cause of drug-resistant tuberculosis in Kazakhstan.

Setting: Nine Kazakhstan oblasts, 2001.

Objective: To analyse the genetic relationship of drug-resistant Mycobacterium tuberculosis strains from Kazakhstan and to determine the frequency of the Beijing genotype.

Design: All drug-resistant smear-positive cases identified in nine oblasts during the 2001 nationwide drug resistance survey were analysed by IS6110 fingerprinting and spoligotyping.