Publications by authors named "Quzhen Danzeng"

Ticks are specialized ectoparasites that feed on blood, causing physical harm to the host and facilitating pathogen transmission. The genus Haemaphysalis contains vectors for numerous infectious agents. These agents cause various diseases in humans and animals.

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Lung adenocarcinoma (LUAD), a prominent lung cancer subtype, has an underexplored relationship with PANoptosis, a recently discovered mode of tumour cell death. This study incorporated iron death, copper death, scorch death, necrotizing apoptosis and bisulfide death into a pan-death gene set (PANoptosis) and conducted single-cell analysis of scRNA-seq data from 11 LUAD samples. Differentially expressed genes were identified, and Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were performed.

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Existing manual deworming programs launched have made great progress in reducing the infection rate of domestic dogs, but significant challenges remain in scattered nomadic communities inhabiting the Tibetan Plateau. The low deworming frequency and low levels of coverage were responsible for the high infection rate of spp. among dogs.

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Background: Echinococcosis is a neglected zoonotic parasitic disease caused echinococcus parasitizes, poseing a significant economic burden on both humans and animals. There are limited studies on echinococcosis in China, especially Xizang Autonomous Region, although the area is endemic area for echinococcosis. The study aimed to provide information for strategic prevention against this disease.

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Background: At present, there is no available delirium translated assessment method for 3.3 million Tibetans. This study aimed to provide a method for delirium assessment for Tibetan patients speaking this language by validating a translation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).

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Purpose: Early application of protease inhibitors through the intestinal lumen could increase survival following experimental shock by blocking the pancreatic digestive enzymes. Hence, it was hypothesized that two-route injection (intraintestinal + intravenous) of ulinastatin (UTI), a broad-spectrum protease inhibitor, could better alleviate intestinal injury than single-route injection (either intravenous or intraintestinal).

Methods: A sepsis model induced by lipopolysaccharide on rats was established.

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Article Synopsis
  • Septic shock is a severe form of sepsis that significantly increases mortality due to serious circulatory and metabolic problems.
  • A study of 52 critically ill patients evaluated the effectiveness of the SOFA score in predicting 28-day mortality in those undergoing pulse indicator contour continuous cardiac output (PiCCO)-directed goal therapy (PDGT).
  • Results showed that higher SOFA scores in nonsurvivors compared to survivors indicate better predictive accuracy for mortality risk than the APACHE II score, with SOFA demonstrating a strong statistical significance (P < .001).
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Background: We investigated the safety of therapeutic hypothermia during intervention in infants with hypoxic-ischemic encephalopathy (HIE).

Methods: The MEDLINE, EMBASE, PubMed, and the Cochrane Central Register of Controlled Trials from onset to November 30, 2016 were searched for studies on perinatal HIE. Randomized controlled trials comparing the use of therapeutic hypothermia with normothermia for perinatal HIE were included in the study.

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