Publications by authors named "Quynh Tran Thuy Huong"

Article Synopsis
  • * A mouse model, Cd79a-Tsc1 KO, was used to study how mTOR impacts the formation of cysts, showing cyst development by 1 week and full PKD by 4 weeks due to continued cell division.
  • * The study suggests that overactivation of mTORC1 interferes with kidney cell morphogenesis and the proper orientation of cell division, hinting at a crucial role of mTOR and cilium signaling in cyst formation.
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Background: Breastfeeding is beneficial to both mother and infant. However, overlap of lactation with pregnancy and short recuperative intervals may impact mothers nutritionally. We aimed to investigate the possible effects of pregnancy during breastfeeding.

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Background: Since the COVID-19 pandemic began, there have been concerns related to the preparedness of healthcare workers (HCWs). This study aimed to describe the level of awareness and preparedness of hospital HCWs at the time of the first wave.

Methods: This multinational, multicenter, cross-sectional survey was conducted among hospital HCWs from February to May 2020.

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Background: Tuberculous meningitis (TBM), manifests as the most severe involvement of the nervous system by Mycobacterium tuberculosis, it has a high mortality rate and a spectrum of systemic and neurological complications that can lead to debilitating or fatal sequelae, whereas hyponatremia is the commonly encountered life-threatening electrolyte disturbance. Thus, our study aimed to determine the prevalence, risk factors and differences in outcomes of hyponatremia in TBM.

Methods: This systematic review was registered in PROSPERO (CRD42018088089).

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Article Synopsis
  • IgA nephropathy (IgAN) is a common kidney disease with some familial cases, and this study investigates the outcomes of patients with a family history of renal disorders.
  • The study followed 467 patients over an average of 8.9 years to compare those with positive family histories (11.6% of the sample) to those without.
  • Results indicated that patients with a positive family history had a lower initial kidney function (eGFR) and were at a greater risk for poor outcomes, highlighting familial history as a significant factor in IgAN prognosis.
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  • Asymptomatic leishmaniasis significantly contributes to the ongoing transmission of Leishmania within endemic communities, complicating efforts to eliminate the disease.
  • A systematic review and meta-analysis of 111 articles found an overall prevalence of 11.2% for asymptomatic leishmaniasis in the general population, with higher rates (36.7%) in those living with symptomatic patients.
  • The study revealed that 64.9% of individuals with leishmaniasis were asymptomatic, and males were more likely to develop symptoms, with a notable prevalence remaining stable over the past 40 years.
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Current evidence indicates that nutritional status in newborns, especially the duration of breastfeeding, plays a key role in the pathogenesis of autism spectrum disorder. We aimed to systematically review and meta-analyze relevant studies with findings of an association between autism spectrum disorder and breastfeeding patterns, and undertook an extensive dose-response analysis to interpret the results more accurately. Ten electronic databases and manual search of reference lists were used to identify relevant studies in September 2018.

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